* Games should support the FIRE 2 button for gamepads/joysticks. Maybe the player character needs to be able to jump, and then UP is used for this. And that is ok. Just don't forget to include the FIRE 2 button for jumping as well.
* Consider supporting AMX Mouse (or compatibles such as Bryce's USB mouse hardware) and Symbiface 2 Mouse where it makes sense in the game. Movement could also be used for moving to the wanted menu item and clicking the mouse button to select.